Whats the Best Time of Day to Take Blood Pressure Medication

Does the fourth dimension yous take your medicine matter?

Could irresolute the time of solar day you accept blood pressure medications improve their effectiveness? Professor Tom MacDonald tells Thembi Nkala how he intends to find out.

Loftier blood pressure (hypertension) affects one in four adults in the Uk. Having high blood pressure, persistently equal to or above 140/90mmHg, significantly increases your risk of cardiovascular disease, including heart attack and stroke. Hypertension, which is increasingly common with age, poses a significant threat to the health of millions of people just, once diagnosed, can exist managed well with medications.

At present, a team of tiptop researchers from across the United kingdom, led by Professor Tom MacDonald and backed by a BHF inquiry grant worth more than than £1m, aims to find out if taking blood pressure tablets in the morn or the evening has more of an touch on on your cardiovascular health.

Why might the fourth dimension of day matter when taking your blood force per unit area medications?

The purpose of our research is to plant whether dark-fourth dimension dosing is better (or worse) than morning treatment

We know that taking claret force per unit area tablets in the morning is beneficial in controlling high blood pressure, but more recent findings (enabled by the utilize of 24-60 minutes blood pressure monitoring) advise that night-fourth dimension dosing may have an even meliorate effect. Patients with hypertension whose blood force per unit area dips during the night tend to feel fewer cardiovascular events compared with those whose blood pressure barely decreases. Essentially, those with constant high blood pressure day and nighttime don't do so well.

The purpose of our research is to study patients taking in one case-a-day blood pressure level medication and establish whether night-time dosing is ameliorate (or worse) than morning handling in preventing events such as heart attacks, stroke and deaths related to diseases of the heart and circulation. Participants will be randomly allocated into 2 groups; one volition take their blood pressure tablets at night, while the other group takes theirs in the morning.

When should I take my blood pressure level medication?

Currently, at that place is no set guidance on when you should have your blood pressure tablets. What is important is that you lot take them regularly as your doctor has recommended for you.

Tin can you tell united states virtually the recruitment process for this study?

Recruitment to the study is open up to anyone who takes tablets for blood pressure level once daily. We hope to recruit more than x,000 participants of equally varied demographics as possible and report them over a catamenia of five years. A report of this size and duration should enable united states of america to know with confidence whether or not the time you take your medication is important. Patients are invited through GP surgeries, hospitals and social media from all across the UK to participate.

£ane meg is the value of the BHF grant for Professor Tom MacDonald'due south research

Patients who currently take blood pressure medication twice daily (morning time and evening), those who do nighttime-shift piece of work or those in other clinical trials at nowadays can't take part in this report.

Participants too demand to have regular admission to the internet, equally this study is done by email and also through a link to a secure website. Although this excludes a certain proportion of patients, for practical and fiscal reasons it would be difficult to do a study of this size in the conventional way, where participants are seen by a clinician regularly. Previous studies that have used the spider web-based method found that correspondence was high-quality and toll-effective.

Can Center Matters readers take part?

If they accept an e-mail account and are interested in beingness part of this study, they can visit timestudy.co.britain or call 0800 917 3509 for detailed information that they should know earlier deciding whether to sign up. Subsequently registering an interest, they'll exist sent an email to confirm their desire to participate. We will then request explicit consent for us to access and use the data we demand. This includes relevant medical records from GP surgeries and hospitals. We also ask for permission to write to the GP or a nominated next of kin in case we can't become concord of participants.

Will the participants' records be safe?

Even getting a modest effect within our study could imply an incredible do good to the population at big

Nosotros are using a website that has been set up for this study and the data is stored as securely every bit possible. We take to point that we have secure data protection measures before this study is approved. We employ estimator experts (known every bit upstanding hackers) who deliberately attack our calculator security arrangement to exam for any flaws we might accept disregarded. Personal information will be treated with the strictest confidentiality past the staff working on the study, and publications of the results of the study volition not include any identifiable details nearly participants.

Can a participant withdraw from the report at any time?

Yes. Equally, if during the enquiry at that place was an enormous upshot difference between the groups, we may be instructed to discontinue the study, every bit it would be unethical to bear on.

How could this research help patients?

If this study showed that the fourth dimension of 24-hour interval you take your blood pressure medication can have an effect on events such as strokes and heart attacks, it would provide enormous wellness benefits. Even getting a pocket-sized effect within our study could imply an incredible do good to the population at large. We'd like to thank the BHF, which has funded this study, and the British Hypertension Social club, which is co-ordinating it.

Professor Tom MacDonald

Professor MacDonald is a Professor of Clinical Pharmacology and Pharmacoepidemiology at Dundee University, besides every bit a Consultant Physician at Ninewells Hospital and Medical School. Professor MacDonald is also President of the British Hypertension Guild.

wrightdeffords.blogspot.com

Source: https://www.bhf.org.uk/informationsupport/heart-matters-magazine/research/timing-of-medications

Share this post